Endothelial Dysfunction in the Brain

Brain endothelial dysfunction in cerebral adrenoleukodystrophy.

See Aubourg (doi:10.1093/awv271) for a scientific commentary on this article.X-linked adrenoleukodystrophy is caused by mutations in the ABCD1 gene leading to accumulation of very long chain fatty acids. Its most severe neurological manifestation is cerebral adrenoleukodystrophy. Here we demonstrate that progressive inflammatory demyelination in cerebral adrenoleukodystrophy coincides with bloo...

CARDIAC ELECTRICAL DYSFUNCTION IN ACUTE BRAIN LESIONS

This study briefly reviews the heart abnormalities in diverse intracranial pathologies, including strokes, spontaneous and traumatic subarachnoid hemorrhage and intracranial hemorrhage, and presents the results of a one-year prospective study of heart abnormalities in patients with moderate to severe head injuries and subarachnoid hemorrhage. Different abnormalities such as: QT -interval, T...

Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

The roles of potassium channels in contractile response to urotensin-II in mercury chloride induced endothelial dysfunction in rat aorta

Urotensin-II (U-II), the most potent vasoconstrictor that has recently been recognized as a new candidate in cardiovascular dysfunction, might exert vasoconstriction through, at least partially, potassium channels that are predominant in both endothelial and vascular smooth muscle cells (VSMCs). The present study was designed to evaluate the roles of potassium channels in vascular responses to ...

cardiac electrical dysfunction in acute brain lesions

this study briefly reviews the heart abnormalities in diverse intracranial pathologies, including strokes, spontaneous and traumatic subarachnoid hemorrhage and intracranial hemorrhage, and presents the results of a one-year prospective study of heart abnormalities in patients with moderate to severe head injuries and subarachnoid hemorrhage. different abnormalities such as: qt -interval, t -wa...